The polycystic kidney or polycystic kidney disease is a progressive genetic disease that is identified by the appearance of cysts in the kidney or in both kidneys and that may also affect the liver, pancreas, and, sometimes, the heart and brain.

People with a family member who has suffered a cerebral aneurysm are more likely to develop it than people with no family history.

Fibrous dysplasia is a disorder that affects the bones. It is a pathology defined as the replacement of normal bone with a mixture of  immature fibrous tissue and immature bone fragments. The cervical spine and skull are two of the most common areas affected by monostotic fibrous dysplasia.

Aortic coarctation is a congenital disease that causes narrowing of part of the aorta. This pathology is associated with other birth defects such as facial hypertrophy and renal artery stenosis and global angiologic insufficiency.

Marfan disease or syndrome, is a disorder of genetic origin, which affects the connective tissue and which tends to cause alterations to the eyes, skeleton, heart and blood vessels.