The Hospital Clínic de Barcelona Hematopoietic Stem Cell Transplant (HSCT) Program started on 12 June 1976 and the clinic became the first Spanish center to perform an allogeneic transplant. Over the past thirty plus years, more than 1900 transplants have been performed with 1000 of these being allogeneic transplants. Today between 80 and 90 transplants are performed each year, with more than half of these being allogeneic transplants and many of them being highly complex. The attached diagram shows the development of this activity over recent years.

HSCT Program Resources

  • Personnel

Our program is fortunate to have a medical team that is 100% dedicated to HSCT. As a result, our patients are always seen by the same team of physicians throughout the entire procedure, from their initial hospitalization phase to subsequent monitoring at the Day Hospital or Outpatients Clinic.

We also have a team of specially trained hospital nurses who have extensive experience in the care of these patients with a nurse-to-patient ratio that is never more than 1:5. Moreover we have a team of home nurses that is highly specialized in this type of care. These facts are crucial for ensuring the high quality of care required for a procedure of this complex nature.

  • Material resources

The transplant unit has 18 rooms with filtered air that allow ISO Class 8 environmental isolation and these rooms have all the necessary equipment to make it possible to provide high-level medical care and meet the patient's basic needs. There is also a day hospital specifically for HSCT recipients that is open 7 days a week with one of the HSCT program specialists always on duty.

Another feature is an apheresis unit that is able to perform a minimum of three procedures a week and provide all the single donor transfusion support that our patients require. A graft processing, handling and cryopreservation unit is especially equipped to perform all types of cell screening. Finally, there is a radiotherapy unit that is prepared to administer total body irradiation if patients require it.

  • International accreditation

The Hospital Clínic HSCT program is one of the few programs to have JACIE international accreditation for HSCT programs. This guarantees the quality of care of all program procedures performed at our facilities.

  • Activity

The progressive improvement in our country's health system has meant that more and more centers are performing conventional hematopoietic stem cell transplants. That is why our program, in compliance with the usual line of advance of our institution, has directed its efforts towards highly complex transplant programs. Furthermore, in addition to conventional transplants for all types of diseases, we are also developing other lines of care.


Lines of care

  • Autologous transplant for unusual diseases, especially:

    - Autoimmune diseases. Multiple sclerosis, Crohn's disease and lupus erythematosus. We are the only center in Spain taking part in international studies for the treatment of these diseases.

    - Plasma cell dyscrasias. Our center is the most experienced center in the country regarding the treatment of light chain diseases or scleromyxedema.

  • Allogeneic transplant from an unrelated donor.

This therapeutic method now represents more than half of all allogeneic transplants and the center is responsible for the highest number of these procedures per year in Spain. Also, more and more patients are being treated by umbilical cord transplant due to not being able to locate a compatible volunteer donor.

  • Allogeneic transplant for uncommon diseases.

Given our center's advanced specialization in hematological diseases as a result of us being a national and international referral site, lines of transplant care have been developed for patients with diseases that are not curable by any other means, such as idiopathic myelofibrosis, multiple myeloma, aggressive lymphomas, chronic lymphocytic leukemia or paroxysmal nocturnal hemoglobinuria, for whom this therapeutic option has only recently been made available.