{"id":2360,"date":"2021-11-23T08:45:34","date_gmt":"2021-11-23T08:45:34","guid":{"rendered":"http:\/\/www.barnaclinic.com\/blog\/ca\/?p=2360"},"modified":"2021-12-23T08:37:06","modified_gmt":"2021-12-23T08:37:06","slug":"terapies-car-t-best-in-class","status":"publish","type":"post","link":"https:\/\/www.barnaclinic.com\/blog\/ca\/blog\/terapies-car-t-best-in-class\/","title":{"rendered":"La Unitat de Ter\u00e0pies CAR-T del Cl\u00ednic rep el premi ‘Best in Class’ de Gaceta M\u00e9dica"},"content":{"rendered":"

La revista\u00a0Gaceta M\u00e9dica<\/a> ha anunciat els guanyadors anuals dels seus\u00a0premis \u2018Best in Class\u2019<\/strong><\/a>, una iniciativa a trav\u00e9s de la qual volen recon\u00e8ixer l’excel\u00b7l\u00e8ncia sanit\u00e0ria dels hospitals i les unitats que han sobresortit en la seva aposta per la qualitat assistencial. Entre els guardonats d’aquesta edici\u00f3 va estar la Unitat de Ter\u00e0pies CAR-T<\/a> de l’Hospital Cl\u00ednic<\/strong>, que tamb\u00e9 ofereix els seus serveis\u00a0a barnacl\u00ednic+. Pel Dr. \u00c1lvaro Urbano-Ispizua<\/strong><\/a>, cap de Servei d’Hematologia de l’Hospital Cl\u00ednic<\/a>, l’\u00e8xit de la unitat es basa a disposar d’un equip de persones molt important, \u201camb una dedicaci\u00f3 extraordin\u00e0ria al projecte, i en un suport institucional clar\u201d .<\/p>\n

<\/p>\n

La Unitat de Ter\u00e0pies CAR-T<\/h2>\n

La Unitat de CAR-T \u00e9s un equip multidisciplinari que reuneix m\u00e9s de 180 professionals, entre els quals hi ha hemat\u00f2legs<\/a>, farmac\u00f2legs, neur\u00f2legs<\/a>, metges intensivistes i immun\u00f2legs entre d’altres. Des que es va posar en funcionament, fa m\u00e9s de 10 anys, ja s’han tractat en aquesta unitat m\u00e9s de cent pacients amb productes propis, com ara la ter\u00e0pia CAR-T ARI-001<\/strong><\/a>, aprovada recentment per part de l’Ag\u00e8ncia Espanyola del Medicament (AEMPS)<\/a>, per\u00f2 tamb\u00e9 molts altres amb altres productes comercials.<\/p>\n

Actualment \u00e9s un dels centres autoritzats pel Sistema Nacional de Salut per a l’administraci\u00f3 comercial de productes CAR-T (\u00e9s el que va obtenir la m\u00e0xima puntuaci\u00f3 de tots els centres autoritzats), estant actualment acreditats per a l’administraci\u00f3 dels dos CARTs comercials disponibles<\/strong> ( Yescarta de Kite-Gilead i Kymriah de Novartis). Aquestes acreditacions han habilitat el centre a tractar pacients amb limfomes difusos de c\u00e8l\u00b7lules grans B, limfomes primaris mediast\u00ednics, limfomes fol\u00b7liculars transformats, i leuc\u00e8mia aguda limfobl\u00e0stica dins un programa de tractaments CAR-T aprovats<\/strong>.<\/p>\n

\n

LI POT INTERESSAR\u2026<\/h4>\n

–<\/em> El programa de CAR-T a barnacl\u00ednic+<\/a><\/h4>\n

–<\/em> L\u2019AEMPS aprova l\u2019\u00fas d\u2019una ter\u00e0pia de CAR-T desenvolupada pel Grup Hospital Cl\u00ednic per al tractament d\u2019un tipus de leuc\u00e8mia<\/a><\/h4>\n

–<\/em> El Grup Hospital Cl\u00ednic desenvolupa un segon CAR-T per al mieloma m\u00faltiple resistent al tractament<\/a><\/h4>\n<\/div>\n

Un dels principals objectius que es persegueix amb la Unitat de CAR-T<\/strong> de l’Hospital Cl\u00ednic \u00e9s acostar aquest tractament de les CAR-T<\/strong> a pacients que tenien poques opcions terap\u00e8utiques, ampliant aix\u00ed les opcions de tractar els tumors i aix\u00ed oferir als pacients bones alternatives de tractament.<\/p>\n

Qu\u00e8 s\u00f3n les ter\u00e0pies CAR-T?<\/h2>\n

En la lluita contra el c\u00e0ncer cada vegada est\u00e0 adquirint m\u00e9s protagonisme la immunoter\u00e0pia<\/a><\/strong>. \u00c9s un enfocament centrat a utilitzar el propi sistema immunitari del pacient per combatre les c\u00e8l\u00b7lules tumorals. La ter\u00e0pia CAR-T<\/strong><\/a> \u00e9s el resultat d’unir aquesta\u00a0immunoter\u00e0pia<\/a><\/strong> amb dos tipus m\u00e9s avan\u00e7ats de ter\u00e0pies: la ter\u00e0pia cel\u00b7lular<\/strong> i la ter\u00e0pia gen\u00e8tica<\/strong>. Han suposat tota una irrupci\u00f3 en l’abordatge de malalties amb una alta mortalitat com la leuc\u00e8mia limfobl\u00e0stica aguda, els limfomes agressius de c\u00e8l\u00b7lules B o el mieloma m\u00faltiple.<\/p>\n

\n

LI POT INTERESSAR\u2026<\/h4>\n

–<\/em> \u00bfQu\u00e9 es la INMUNOTERAPIA para el c\u00e1ncer?<\/a><\/h4>\n<\/div>\n

S’aconsegueix aix\u00ed una de les opcions m\u00e9s personalitzades que existeixen en el tractament del c\u00e0ncer<\/strong>. B\u00e0sicament consisteix a extreure un tipus de c\u00e8l\u00b7lula concret del pacient, els limf\u00f2cits T, uns gl\u00f2buls blancs que s’encarreguen de la resposta immunit\u00e0ria. Aix\u00f2 es fa en una primera fase mitjan\u00e7ant una extracci\u00f3 de sang.<\/p>\n

Posteriorment al laboratori aquests limf\u00f2cits s\u00f3n modificats gen\u00e8ticament per aconseguir que se’n potenci\u00ef la resposta immunit\u00e0ria. Aix\u00ed \u00e9s com s’obtenen les c\u00e8l\u00b7lules CART-T, que reconeixen i ataquen les c\u00e8l\u00b7lules tumorals. Finalment, aquestes es tornen a introduir al pacient perqu\u00e8 identifiquin selectivament i destrueixin les c\u00e8l\u00b7lules malignes sense danyar les sanes.<\/p>\n

Imatge: Gaceta M\u00e9dica<\/a><\/small><\/p>\n

\n
\n

VOL CONTACTAR AMB EL NOSTRE SERVEI D’HEMATOLOGIA O DESITJA INFORMACI\u00d3 SOBRE EL NOSTRE PROGRAMA DE CAR-T?<\/span><\/h4>\n

DEMANAR CITA PRESENCIAL<\/a> |\u00a0SOL\u00b7LICITAR TELEVISITA<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

La revista\u00a0Gaceta M\u00e9dica ha anunciat els guanyadors anuals dels seus\u00a0premis \u2018Best in Class\u2019, una iniciativa a trav\u00e9s de la qual volen recon\u00e8ixer l’excel\u00b7l\u00e8ncia sanit\u00e0ria dels hospitals i les unitats que han sobresortit en la seva aposta per la qualitat assistencial. Entre els guardonats d’aquesta edici\u00f3 va estar la Unitat de Ter\u00e0pies CAR-T de l’Hospital Cl\u00ednic, […]<\/p>\n","protected":false},"author":2,"featured_media":2359,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1124,413,829,434],"tags":[582,831,1184],"yoast_head":"\nLa Unitat de CAR-T del Cl\u00ednic, premi 'Best in Class' de Gaceta M\u00e9dica<\/title>\n<meta name=\"description\" content=\"Entre els guanyadors d'aquesta edici\u00f3 del 'Best in Class' hi ha la Unitat de Ter\u00e0pies CAR-T de l'Hospital Cl\u00ednic, que ofereix serveis tamb\u00e9 a barnacl\u00ednic+\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.barnaclinic.com\/blog\/ca\/blog\/terapies-car-t-best-in-class\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" 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